Victoria Police are investigating two suspected arson incidents in Melbourne after a medical centre in the city's north-west was extensively damaged and two vehicles were set alight outside a home in the south-east.

The first incident occurred at the Moonee Vale Clinic on Shuter Street in Moonee Ponds during the early hours of Tuesday, 27 October. Police said offenders allegedly broke a front window before using an accelerant to start a fire shortly after 2am.

The blaze caused extensive internal damage to the clinic from fire and smoke. The medical centre provides general practice services, including women's health, cosmetic treatments and skin cancer care.

The damage is likely to disrupt services for patients who rely on the clinic for appointments and ongoing medical care. Investigators are examining the circumstances surrounding the break-in and fire to determine who was responsible and whether the incident was deliberately planned.

Police are also investigating whether the latest attack could be connected to earlier arson incidents at a neighbouring beauty salon. However, investigators have not confirmed a connection, and the possibility remains under examination.

A second suspected arson attack occurred approximately an hour earlier in Brighton, in Melbourne's south-east.

Police said offenders allegedly rammed the front gate of a home on Manor Street at about 1:20am. An accelerant was then allegedly poured along the driveway towards the residence and over two parked vehicles, which were subsequently set alight.

Both cars were destroyed in the fire. Residents of the property were not injured, according to police.

The circumstances of the Brighton incident have prompted investigators to examine whether the property was deliberately targeted. Police have not publicly established a motive or identified suspects in the available report.

An arson chemist was expected to attend both locations on Tuesday to assist with the investigations. Specialist examinations can help establish how fires started, identify potential accelerants and assess physical evidence collected at the scenes.

Investigators are also seeking information from members of the public who may have witnessed suspicious activity in either area during the early hours of Tuesday morning. Dashcam footage, security-camera recordings and other relevant information could help police establish the movements of people or vehicles around the locations.

Authorities have asked anyone with information to contact Crime Stoppers.

The two incidents occurred at separate locations and police have not confirmed that they are connected. It is important not to assume a common offender or motive until investigators establish the facts.

Suspected arson can create serious risks for nearby residents, workers, emergency responders and surrounding properties. Beyond the immediate danger posed by flames and smoke, fires can cause substantial financial losses and disrupt essential local services.

The investigation into both incidents remains ongoing, and police are continuing to gather evidence to determine the circumstances of each fire.