Queensland Police have launched a homicide investigation after a man died following an incident involving a vehicle in Fernvale, west of Brisbane, on Sunday evening.

Emergency services were called to Stoneywood Street in Fernvale shortly before 6pm after reports that a man had been struck by a vehicle. When officers and paramedics arrived, they found a 50-year-old man unresponsive at the scene.

Queensland Ambulance Service said the man had suffered serious injuries to his head, chest, arm and leg. Despite the emergency response, he died at the scene.

Police subsequently arrested a 45-year-old woman in connection with the incident. Investigators said the man and woman knew each other.

The circumstances surrounding the death remain under investigation. Police have classified the investigation as a homicide inquiry while detectives work to establish exactly what happened before and during the incident.

Fernvale is located in the Somerset Region, west of Brisbane. The incident has prompted a significant police investigation as detectives examine the circumstances surrounding the vehicle collision and the relationship between the people involved.

Police investigations following a suspected homicide generally involve examining the location where the incident occurred, speaking with witnesses and gathering forensic and other evidence. Investigators may also review available information about the people involved to establish a timeline of events.

Authorities have not publicly released further details about what led to the man being struck, and no conclusions should be drawn about the circumstances beyond the information confirmed by police.

The incident is one of several serious incidents being investigated across Queensland on Monday. Police have continued to urge members of the public with relevant information to come forward when they may be able to assist an investigation.

The Fernvale case remains active, and further information may be released as investigators establish more details about the circumstances surrounding the man's death.